Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy

Background: Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas cardiomyopathy (CCC), an inflammatory dilated cardiomyopathy that is the most important clinical consequence of T. cruzi infection, while...

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Publicado en:Front Immunol
Autores principales: Frade-Barros, Amanda Farage, Ianni, Barbara Maria, Cabantous, Sandrine, Pissetti, Cristina Wide, Saba, Bruno, Lin-Wang, Hui Tzu, Buck, Paula, Marin-Neto, José Antonio, Schmidt, André, Dias, Fabrício, Hirata, Mario Hiroyuki, Sampaio, Marcelo, Fragata, Abílio, Pereira, Alexandre Costa, Donadi, Eduardo, Rodrigues, Virmondes, Kalil, Jorge, Chevillard, Christophe, Cunha-Neto, Edecio
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358543/
https://ncbi.nlm.nih.gov/pubmed/32733459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01386
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