Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy

Background: Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas cardiomyopathy (CCC), an inflammatory dilated cardiomyopathy that is the most important clinical consequence of T. cruzi infection, while...

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Vydáno v:Front Immunol
Hlavní autoři: Frade-Barros, Amanda Farage, Ianni, Barbara Maria, Cabantous, Sandrine, Pissetti, Cristina Wide, Saba, Bruno, Lin-Wang, Hui Tzu, Buck, Paula, Marin-Neto, José Antonio, Schmidt, André, Dias, Fabrício, Hirata, Mario Hiroyuki, Sampaio, Marcelo, Fragata, Abílio, Pereira, Alexandre Costa, Donadi, Eduardo, Rodrigues, Virmondes, Kalil, Jorge, Chevillard, Christophe, Cunha-Neto, Edecio
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358543/
https://ncbi.nlm.nih.gov/pubmed/32733459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01386
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