Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy

Background: Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas cardiomyopathy (CCC), an inflammatory dilated cardiomyopathy that is the most important clinical consequence of T. cruzi infection, while...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Frade-Barros, Amanda Farage, Ianni, Barbara Maria, Cabantous, Sandrine, Pissetti, Cristina Wide, Saba, Bruno, Lin-Wang, Hui Tzu, Buck, Paula, Marin-Neto, José Antonio, Schmidt, André, Dias, Fabrício, Hirata, Mario Hiroyuki, Sampaio, Marcelo, Fragata, Abílio, Pereira, Alexandre Costa, Donadi, Eduardo, Rodrigues, Virmondes, Kalil, Jorge, Chevillard, Christophe, Cunha-Neto, Edecio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358543/
https://ncbi.nlm.nih.gov/pubmed/32733459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01386
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