Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning

BACKGROUND: P301S tau transgenic mice show age-dependent accumulation of neurofibrillary tangles in the brainstem, hippocampus, and neocortex, leading to neuronal loss and cognitive deterioration. However, there is hitherto only sparse documentation of the role of neuroinflammation in tau mouse mode...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Eckenweber, Florian, Medina-Luque, Jose, Blume, Tanja, Sacher, Christian, Biechele, Gloria, Wind, Karin, Deussing, Maximilian, Briel, Nils, Lindner, Simon, Boening, Guido, von Ungern-Sternberg, Barbara, Unterrainer, Marcus, Albert, Nathalie L., Zwergal, Andreas, Levin, Johannes, Bartenstein, Peter, Cumming, Paul, Rominger, Axel, Höglinger, Günter U., Herms, Jochen, Brendel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358201/
https://ncbi.nlm.nih.gov/pubmed/32660586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01883-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados