EGFR activation attenuates the mechanical threshold for integrin tension and focal adhesion formation

Mechanical forces, growth factors and the extracellular matrix all play crucial roles in cell adhesion. To understand how epidermal growth factor receptor (EGFR) impacts the mechanics of adhesion, we employed tension gauge tether (TGT) probes displaying the integrin ligand cRGDfK and quantified inte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Sci
Egile Nagusiak: Rao, Tejeshwar C., Ma, Victor Pui-Yan, Blanchard, Aaron, Urner, Tara M., Grandhi, Shreya, Salaita, Khalid, Mattheyses, Alexa L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists Ltd 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358133/
https://ncbi.nlm.nih.gov/pubmed/32546532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.238840
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