Slc26a9(P2ACre): a new CRE driver to regulate gene expression in the otic placode lineage and other FGFR2b-dependent epithelia

Pan-otic CRE drivers enable gene regulation throughout the otic placode lineage, comprising the inner ear epithelium and neurons. However, intersection of extra-otic gene-of-interest expression with the CRE lineage can compromise viability and impede auditory analyses. Furthermore, extant pan-otic C...

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Vydáno v:Development
Hlavní autoři: Urness, Lisa D., Wang, Xiaofen, Li, Chaoying, Quadros, Rolen M., Harms, Donald W., Gurumurthy, Channabasavaiah B., Mansour, Suzanne L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2020
Témata:
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358128/
https://ncbi.nlm.nih.gov/pubmed/32541002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.191015
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