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Macromolecular Crowding Enhances the Detection of DNA and Proteins by a Solid-State Nanopore

[Image: see text] Nanopore analysis of nucleic acid is now routine, but detection of proteins remains challenging. Here, we report the systematic characterization of the effect of macromolecular crowding on the detection sensitivity of a solid-state nanopore for circular and linearized DNA plasmids,...

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Detalhes bibliográficos
Publicado no:Nano Lett
Main Authors: Chau, Chalmers C., Radford, Sheena E., Hewitt, Eric W., Actis, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357865/
https://ncbi.nlm.nih.gov/pubmed/32559088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c02246
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