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Detection and Quantification of Methylation in DNA using Solid-State Nanopores
Epigenetic modifications in eukaryotic genomes occur primarily in the form of 5-methylcytosine (5 mC). These modifications are heavily involved in transcriptional repression, gene regulation, development and the progression of diseases including cancer. We report a new single-molecule assay for the...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593219/ https://ncbi.nlm.nih.gov/pubmed/23474808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01389 |
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