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Macromolecular Crowding Enhances the Detection of DNA and Proteins by a Solid-State Nanopore

[Image: see text] Nanopore analysis of nucleic acid is now routine, but detection of proteins remains challenging. Here, we report the systematic characterization of the effect of macromolecular crowding on the detection sensitivity of a solid-state nanopore for circular and linearized DNA plasmids,...

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Bibliografische gegevens
Gepubliceerd in:Nano Lett
Hoofdauteurs: Chau, Chalmers C., Radford, Sheena E., Hewitt, Eric W., Actis, Paolo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2020
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357865/
https://ncbi.nlm.nih.gov/pubmed/32559088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.nanolett.0c02246
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