Φορτώνει......
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
Applications of adenine base editors (ABEs) have been constrained by the limited compatibility of the deoxyadenosine deaminase component with Cas homologs other than SpCas9. We evolved the deaminase component of ABE7.10 using phage-assisted non-continuous and continuous evolution (PANCE and PACE), r...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Biotechnol |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7357821/ https://ncbi.nlm.nih.gov/pubmed/32433547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-0453-z |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|