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Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases

Ancestral sequence reconstruction and resurrection provides useful information for protein engineering, yet its alliance with directed evolution has been little explored. In this study, we have resurrected several ancestral nodes of fungal laccases dating back ∼500 to 250 million years. Unlike moder...

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Bibliografiset tiedot
Julkaisussa:Appl Environ Microbiol
Päätekijät: Gomez-Fernandez, Bernardo J., Risso, Valeria A., Rueda, Andres, Sanchez-Ruiz, Jose M., Alcalde, Miguel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357490/
https://ncbi.nlm.nih.gov/pubmed/32414792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00778-20
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