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Ancestral Resurrection and Directed Evolution of Fungal Mesozoic Laccases

Ancestral sequence reconstruction and resurrection provides useful information for protein engineering, yet its alliance with directed evolution has been little explored. In this study, we have resurrected several ancestral nodes of fungal laccases dating back ∼500 to 250 million years. Unlike moder...

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Bibliografski detalji
Izdano u:Appl Environ Microbiol
Glavni autori: Gomez-Fernandez, Bernardo J., Risso, Valeria A., Rueda, Andres, Sanchez-Ruiz, Jose M., Alcalde, Miguel
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357490/
https://ncbi.nlm.nih.gov/pubmed/32414792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00778-20
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