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3-Difluoroalkyl Quaternary Oxindoles Inhibit Macrophage Pyroptosis by Blocking Inflammasome Recruitment of Caspase-1
[Image: see text] Dysregulation of the inflammatory response is a key driver of many debilitating and costly diseases including immune disorders, cancer, and infection. Pyroptosis is a highly inflammatory form of programmed cell death, triggered by various stimuli and meditated by the activation of...
Shranjeno v:
| izdano v: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2020
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7357214/ https://ncbi.nlm.nih.gov/pubmed/32676145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00070 |
| Oznake: |
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