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A Population Pharmacokinetic and Pharmacodynamic Model of CKD-519
CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor that is being developed for dyslipidemia. Even though CKD-519 has shown potent CETP inhibition, the exposure of CKD-519 was highly varied, depending on food and dose. For highly variable exposure drugs, it is cruci...
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| Publié dans: | Pharmaceutics |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7356970/ https://ncbi.nlm.nih.gov/pubmed/32575566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060573 |
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