Pharmacokinetics, pharmacodynamics and safety of CKD-519, a CETP inhibitor, in healthy subjects

CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor being developed for the treatment of dyslipidemia to raise high-density lipoprotein cholesterol. We investigated the safety, tolerability, pharmacokinetics, and pharmacodynamics of single doses of CKD-519 in health...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Kim, Choon Ok, Oh, Eun Sil, Choi, Chungam, Kim, Yeonjoo, Lee, Sera, Kim, Semi, Park, Min Soo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117885/
https://ncbi.nlm.nih.gov/pubmed/27895466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S120387
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