Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors

To develop new antimicrobial agents, a series of novel thiourea derivatives incorporated with different moieties 2–13 was designed and synthesized and their biological activities were evaluated. Compounds 7a, 7b and 8 exhibited excellent antimicrobial activity against all Gram-positive and Gram-nega...

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Argitaratua izan da:Molecules
Egile Nagusiak: Hashem, Heba E., Amr, Abd El-Galil E., Nossier, Eman S., Elsayed, Elsayed A., Azmy, Eman M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356696/
https://ncbi.nlm.nih.gov/pubmed/32549386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122766
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