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Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors

Ligand-targeted toxins (LTTs) are bioengineered molecules which are composed of a targeting component linked to a toxin that induces cell death once the LTT binds its target. Bispecific targeting allows for the simultaneous targeting of two receptors. In this review, we mostly focus on the epidermal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biomolecules
Egile Nagusiak: Oh, Felix, Modiano, Jaime F., Bachanova, Veronika, Vallera, Daniel A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356355/
https://ncbi.nlm.nih.gov/pubmed/32630411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060956
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