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Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats

Neuronal nicotinic acetylcholine receptor (nAChR)-based therapeutics are sought as a potential alternative strategy to opioids for pain management. In this study, we examine the antinociceptive effects of 3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole (CMPI), a novel pos...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Deba, Farah, Ramos, Kara, Vannoy, Matthew, Munoz, Kemburli, Akinola, Lois S., Damaj, M. Imad, Hamouda, Ayman K.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355939/
https://ncbi.nlm.nih.gov/pubmed/32630476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122923
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