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Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis

Fluostatins, benzofluorene-containing aromatic polyketides in the atypical angucycline family, conjugate into dimeric and even trimeric compounds in the post-biosynthesis. The formation of the C–C bond involves a non-enzymatic stereospecific coupling reaction. In this work, the unusual regio- and en...

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Dettagli Bibliografici
Pubblicato in:Biomolecules
Autori principali: Wang, Yuanqi, Zhang, Changsheng, Zhao, Yi-Lei, Zhao, Rosalinda, Houk, Kendall N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355926/
https://ncbi.nlm.nih.gov/pubmed/32466453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060815
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