The locality dilemma of Sankoff-like RNA alignments

MOTIVATION: Elucidating the functions of non-coding RNAs by homology has been strongly limited due to fundamental computational and modeling issues. While existing simultaneous alignment and folding (SA&F) algorithms successfully align homologous RNAs with precisely known boundaries (global SA&a...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Müller, Teresa, Miladi, Milad, Hutter, Frank, Hofacker, Ivo, Will, Sebastian, Backofen, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Macromolecular Sequence, Structure, and Function
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355259/
https://ncbi.nlm.nih.gov/pubmed/32657398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa431
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