Performance of computational methods for the evaluation of Pericentriolar Material 1 missense variants in CAGI-5

The CAGI-5 PCM1 challenge aimed to predict the effect of 38 transgenic human missense mutations in the Pericentriolar Material 1 (PCM1) protein implicated in schizophrenia. Participants were provided with 16 benign variants (negative controls), 10 hypomorphic, and 12 loss of function variants. Six g...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Hum Mutat
Main Authors: Monzon, Alexander Miguel, Carraro, Marco, Chiricosta, Luigi, Reggiani, Francesco, Han, James, Ozturk, Kivilcim, Wang, Yanran, Miller, Maximilian, Bromberg, Yana, Capriotti, Emidio, Savojardo, Castrense, Babbi, Giulia, Martelli, Pier Luigi, Casadio, Rita, Katsonis, Panagiotis, Lichtarge, Olivier, Carter, Hannah, Kousi, Maria, Katsanis, Nicholas, Andreoletti, Gaia, Moult, John, Brenner, Steven E., Ferrari, Carlo, Leonardi, Emanuela, Tosatto, Silvio C.E.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354699/
https://ncbi.nlm.nih.gov/pubmed/31260570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23856
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki