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Human Cytomegalovirus Mediates Unique Monocyte-to-Macrophage Differentiation through the PI3K/SHIP1/Akt Signaling Network

Blood monocytes mediate the hematogenous dissemination of human cytomegalovirus (HCMV) in the host. However, monocytes have a short 48-hour (h) lifespan and are not permissive for viral replication. We previously established that HCMV infection drives differentiation of monocytes into long-lived mac...

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Detalles Bibliográficos
Publicado en:Viruses
Main Authors: Cojohari, Olesea, Mahmud, Jamil, Altman, Aaron M., Peppenelli, Megan A., Miller, Michael J., Chan, Gary C.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354488/
https://ncbi.nlm.nih.gov/pubmed/32560319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12060652
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