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Human Cytomegalovirus Induces an Atypical Activation of Akt To Stimulate the Survival of Short-Lived Monocytes

Human cytomegalovirus (HCMV) is a pervasive herpesvirus responsible for significant morbidity and mortality among immunodeficient/naive hosts. Following a primary HCMV infection, circulating blood monocytes mediate the systemic spread of the virus. Extending the short 48-h life span of monocytes is...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Cojohari, Olesea, Peppenelli, Megan A., Chan, Gary C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936122/
https://ncbi.nlm.nih.gov/pubmed/27147739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00214-16
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