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Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes.
Primary peripheral blood monocytes are responsible for the hematogenous dissemination of human cytomegalovirus (HCMV) following a primary infection. In order to facilitate viral spread, HCMV extends the naturally short 48-hour lifespan of monocytes by stimulating a non-canonical activation of Akt du...
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| Publicado no: | Antiviral Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7899256/ https://ncbi.nlm.nih.gov/pubmed/30055197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.07.015 |
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