Single chromosomal gains can function as metastasis suppressors and promoters in colon cancer

High levels of cancer aneuploidy are frequently associated with poor prognosis. To examine the relationship between aneuploidy and cancer progression, we analyzed a series of congenic cell lines that harbor single extra chromosomes. We found that across 13 different trisomic cell lines, 12 trisomies...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Vasudevan, Anand, Baruah, Prasamit S., Smith, Joan C., Wang, Zihua, Sayles, Nicole M., Andrews, Peter, Kendall, Jude, Leu, Justin, Chunduri, Narendra Kumar, Levy, Dan, Wigler, Michael, Storchová, Zuzana, Sheltzer, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354079/
https://ncbi.nlm.nih.gov/pubmed/32097652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.01.034
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