Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells

Lysosomes play a key role in regulating cell death in response to cancer therapies, yet little is known on the possible role of lysosomes in the therapeutic efficacy of G-quadruplex DNA ligands (G4L) in cancer cells. Here, we investigate the relationship between the modulation of lysosomal membrane...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Beauvarlet, Jennifer, Nath Das, Rabindra, Alvarez-Valadez, Karla, Martins, Isabelle, Muller, Alexandra, Darbo, Elodie, Richard, Elodie, Soubeyran, Pierre, Kroemer, Guido, Guillon, Jean, Mergny, Jean-Louis, Djavaheri-Mergny, Mojgan
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352983/
https://ncbi.nlm.nih.gov/pubmed/32570977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061621
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki