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Metabolic Landscape of a Genetically Engineered Mouse Model of IDH1 Mutant Glioma

Understanding the metabolic reprogramming of aggressive brain tumors has potential applications for therapeutics as well as imaging biomarkers. However, little is known about the nutrient requirements of isocitrate dehydrogenase 1 (IDH1) mutant gliomas. The IDH1 mutation involves the acquisition of...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Ruiz-Rodado, Victor, Seki, Tomohiro, Dowdy, Tyrone, Lita, Adrian, Zhang, Meili, Han, Sue, Yang, Chunzhang, Cherukuri, Murali K., Gilbert, Mark R., Larion, Mioara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352932/
https://ncbi.nlm.nih.gov/pubmed/32575619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061633
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