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Computer-Aided Ligand Discovery for Estrogen Receptor Alpha

Breast cancer (BCa) is one of the most predominantly diagnosed cancers in women. Notably, 70% of BCa diagnoses are Estrogen Receptor α positive (ERα+) making it a critical therapeutic target. With that, the two subtypes of ER, ERα and ERβ, have contrasting effects on BCa cells. While ERα promotes ca...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bafna, Divya, Ban, Fuqiang, Rennie, Paul S., Singh, Kriti, Cherkasov, Artem
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352601/
https://ncbi.nlm.nih.gov/pubmed/32545494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124193
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