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Benzothiophenone Derivatives Targeting Mutant Forms of Estrogen Receptor-α in Hormone-Resistant Breast Cancers
Estrogen receptor-α positive (ERα(+)) breast cancers represent 75% of all invasive breast cancer cases, while de novo or acquired resistance to ER-directed therapy is also on the rise. Numerous factors contribute to this phenomenon including the recently-reported ESR1 gene mutations such as Y537S, w...
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| Vydáno v: | Int J Mol Sci |
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| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5855801/ https://ncbi.nlm.nih.gov/pubmed/29462880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020579 |
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