Brain Overexpression of Uncoupling Protein-2 (UCP2) Delays Renal Damage and Stroke Occurrence in Stroke-Prone Spontaneously Hypertensive Rats

The downregulation of uncoupling protein-2 (UCP2) is associated with increased brain and kidney injury in stroke-prone spontaneously hypertensive rats (SHRSP) fed with a Japanese style hypersodic diet (JD). Systemic overexpression of UCP2 reduces organ damage in JD-fed SHRSP. We examined the effect...

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Udgivet i:Int J Mol Sci
Main Authors: Busceti, Carla L., Cotugno, Maria, Bianchi, Franca, Forte, Maurizio, Stanzione, Rosita, Marchitti, Simona, Battaglia, Giuseppe, Nicoletti, Ferdinando, Fornai, Francesco, Rubattu, Speranza
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352594/
https://ncbi.nlm.nih.gov/pubmed/32560241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124289
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