High-Speed Atomic Force Microscopy Reveals the Structural Dynamics of the Amyloid-β and Amylin Aggregation Pathways

Individual Alzheimer’s disease (AD) patients have been shown to have structurally distinct amyloid-β (Aβ) aggregates, including fibrils, in their brain. These findings suggest the possibility of a relationship between AD progression and Aβ fibril structures. Thus, the characterization of the structu...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Watanabe-Nakayama, Takahiro, Sahoo, Bikash R., Ramamoorthy, Ayyalusamy, Ono, Kenjiro
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352471/
https://ncbi.nlm.nih.gov/pubmed/32560229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124287
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