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Nanoscale Dynamics of Amyloid Beta-42 Oligomers as Revealed by High-Speed Atomic Force Microscopy
Amyloid β-protein (Aβ) oligomers are emerging as potent neurotoxic species in Alzheimer's disease pathogenesis. Detailed characterization of oligomer structure and dynamics are necessary to develop oligomer-specific therapeutic agents. However, oligomers exist transiently, which complicates the...
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| Publicado no: | ACS Nano |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752618/ https://ncbi.nlm.nih.gov/pubmed/29165985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b05434 |
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