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Nanoscale Dynamics of Amyloid Beta-42 Oligomers as Revealed by High-Speed Atomic Force Microscopy

Amyloid β-protein (Aβ) oligomers are emerging as potent neurotoxic species in Alzheimer's disease pathogenesis. Detailed characterization of oligomer structure and dynamics are necessary to develop oligomer-specific therapeutic agents. However, oligomers exist transiently, which complicates the...

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Detalles Bibliográficos
Publicado en:ACS Nano
Main Authors: Banerjee, Siddhartha, Sun, Zhiqiang, Hayden, Eric Y., Teplow, David B., Lyubchenko, Yuri L.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752618/
https://ncbi.nlm.nih.gov/pubmed/29165985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.7b05434
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