Induction of Autophagy by Vasicinone Protects Neural Cells from Mitochondrial Dysfunction and Attenuates Paraquat-Mediated Parkinson’s Disease Associated α-Synuclein Levels

Mitochondrial dysfunction and disturbed mitochondrial dynamics were found to be common phenomena in the pathogenesis of Parkinson’s disease (PD). Vasicinone is a quinazoline alkaloid from Adhatoda vasica. Here, we investigated the autophagy/mitophagy-enhancing effect of vasicinone and explored its n...

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Bibliografiske detaljer
Udgivet i:Nutrients
Main Authors: Huang, Chih-Yang, Sivalingam, Kalaiselvi, Shibu, Marthandam Asokan, Liao, Po-Hsiang, Ho, Tsung-Jung, Kuo, Wei-Wen, Chen, Ray-Jade, Day, Cecilia-Hsuan, Viswanadha, Vijaya Padma, Ju, Da-Tong
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352463/
https://ncbi.nlm.nih.gov/pubmed/32517337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu12061707
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