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Luminal STIM1 Mutants that Cause Tubular Aggregate Myopathy Promote Autophagic Processes
Stromal interaction molecule 1 (STIM1) is a ubiquitously expressed Ca(2+) sensor protein that induces permeation of Orai Ca(2+) channels upon endoplasmic reticulum Ca(2+)-store depletion. A drop in luminal Ca(2+) causes partial unfolding of the N-terminal STIM1 domains and thus initial STIM1 activat...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7352373/ https://ncbi.nlm.nih.gov/pubmed/32575830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124410 |
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