Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug

OBJECTIVE(S): 4-aminosalicylic acid (4-ASA) is an isomer of mesalazine that has recently been shown to be effective against inflammatory bowel disease (IBD), and more specifically, ulcerative colitis. However, the majority of orally administered 4-ASA is readily and extensively absorbed from the sto...

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Bibliografske podrobnosti
izdano v:Iran J Basic Med Sci
Main Authors: Sadeghi, Fatemeh, Eidizade, Atie, Saremnejad, Farinaz, Hadizadeh, Farzin, Khodaverdi, Elham, Akhgari, Abbas
Format: Artigo
Jezik:Inglês
Izdano: Mashhad University of Medical Sciences 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351447/
https://ncbi.nlm.nih.gov/pubmed/32695295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.41152.9736
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