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Synthesis and evaluation of a prodrug of 5-aminosalicylic acid for the treatment of ulcerative colitis
OBJECTIVE(S): This study is aimed to design and synthesize a prodrug of 5-aminosalicylic acid and evaluate its ameliorative effect on experimental ulcerative colitis (UC). MATERIALS AND METHODS: 5-Aminosalicylic acid-alanine (5-ASA-ALA) was synthesized and characterized. Its stability study was cond...
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| Publicat a: | Iran J Basic Med Sci |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Mashhad University of Medical Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7043877/ https://ncbi.nlm.nih.gov/pubmed/32133064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2019.13991 |
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