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Synthesis and evaluation of a prodrug of 5-aminosalicylic acid for the treatment of ulcerative colitis

OBJECTIVE(S): This study is aimed to design and synthesize a prodrug of 5-aminosalicylic acid and evaluate its ameliorative effect on experimental ulcerative colitis (UC). MATERIALS AND METHODS: 5-Aminosalicylic acid-alanine (5-ASA-ALA) was synthesized and characterized. Its stability study was cond...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Yan, Yan, Ren, Fengling, Wang, Pengchong, Sun, Ying, Xing, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043877/
https://ncbi.nlm.nih.gov/pubmed/32133064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2019.13991
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