Polymorphisms within methotrexate pathway genes: Relationship between plasma methotrexate levels, toxicity experienced and outcome in pediatric acute lymphoblastic leukemia

OBJECTIVE(S): The current study aimed to investigate the relationship of genetic polymorphism and plasma methotrexate (MTX) levels, toxicity experience and event free survival (EFS) in pediatric acute lymphoblastic leukemia (ALL). MATERIALS AND METHODS: The study included 74 ALL patients. Polymerase...

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Bibliografski detalji
Izdano u:Iran J Basic Med Sci
Glavni autori: Esmaili, Mohammad Ali, Kazemi, Ahmad, Faranoush, Mohammad, Mellstedt, Hakan, Zaker, Farhad, Safa, Majid, Mehrvar, Narjes, Rezvany, Mohammad Reza
Format: Artigo
Jezik:Inglês
Izdano: Mashhad University of Medical Sciences 2020
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351433/
https://ncbi.nlm.nih.gov/pubmed/32695297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2020.41754.9858
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