Identifying risk factors for high-dose methotrexate-induced toxicities in children with acute lymphoblastic leukemia

BACKGROUND: Whether monitoring of the methotrexate (MTX) concentrations after high-dose MTX (HD-MTX) infusion can predict toxicities is still controversial, especially when HD-MTX therapy is used in the treatment of children with acute lymphoblastic leukemia (ALL), which is different than the previo...

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Gepubliceerd in:Cancer Manag Res
Hoofdauteurs: Li, Xiao, Sui, Zhongguo, Jing, Fanbo, Xu, Wen, Li, Xiangpeng, Guo, Qie, Sun, Shuhong, Bi, Xiaolin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove 2019
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615715/
https://ncbi.nlm.nih.gov/pubmed/31308758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S207959
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