Improved CNS Control of Childhood Acute Lymphoblastic Leukemia Without Cranial Irradiation: St Jude Total Therapy Study 16

PURPOSE: Despite contemporary treatment, up to 10% of children with acute lymphoblastic leukemia still experience relapse. We evaluated whether a higher dosage of PEG-asparaginase and early intensification of triple intrathecal therapy would improve systemic and CNS control. PATIENTS AND METHODS: Be...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Oncol
Auteurs principaux: Jeha, Sima, Pei, Deqing, Choi, John, Cheng, Cheng, Sandlund, John T., Coustan-Smith, Elaine, Campana, Dario, Inaba, Hiroto, Rubnitz, Jeffrey E., Ribeiro, Raul C., Gruber, Tanja A., Raimondi, Susana C., Khan, Raja B., Yang, Jun J., Mullighan, Charles G., Downing, James R., Evans, William E., Relling, Mary V., Pui, Ching-Hon
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2019
Sujets:
ORIGINAL REPORTS
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351342/
https://ncbi.nlm.nih.gov/pubmed/31657981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.01692
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