Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice

BACKGROUND: Studies have suggested that estrogens may protect mice from AKI. Estrogen sulfotransferase (SULT1E1, or EST) plays an important role in estrogen homeostasis by sulfonating and deactivating estrogens, but studies on the role of SULT1E1 in AKI are lacking. METHODS: We used the renal ischem...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Silva Barbosa, Anne C., Zhou, Dong, Xie, Yang, Choi, You-Jin, Tung, Hung-Chun, Chen, Xinyun, Xu, Meishu, Gibbs, Robert B., Poloyac, Samuel M., Liu, Silvia, Yu, Yanping, Luo, Jianhua, Liu, Youhua, Xie, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351010/
https://ncbi.nlm.nih.gov/pubmed/32424001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019080767
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