Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice

BACKGROUND: Studies have suggested that estrogens may protect mice from AKI. Estrogen sulfotransferase (SULT1E1, or EST) plays an important role in estrogen homeostasis by sulfonating and deactivating estrogens, but studies on the role of SULT1E1 in AKI are lacking. METHODS: We used the renal ischem...

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Detaylı Bibliyografya
Yayımlandı:J Am Soc Nephrol
Asıl Yazarlar: Silva Barbosa, Anne C., Zhou, Dong, Xie, Yang, Choi, You-Jin, Tung, Hung-Chun, Chen, Xinyun, Xu, Meishu, Gibbs, Robert B., Poloyac, Samuel M., Liu, Silvia, Yu, Yanping, Luo, Jianhua, Liu, Youhua, Xie, Wen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Nephrology 2020
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351010/
https://ncbi.nlm.nih.gov/pubmed/32424001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019080767
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