Inhibition of Estrogen Sulfotransferase (SULT1E1/EST) Ameliorates Ischemic Acute Kidney Injury in Mice

BACKGROUND: Studies have suggested that estrogens may protect mice from AKI. Estrogen sulfotransferase (SULT1E1, or EST) plays an important role in estrogen homeostasis by sulfonating and deactivating estrogens, but studies on the role of SULT1E1 in AKI are lacking. METHODS: We used the renal ischem...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Silva Barbosa, Anne C., Zhou, Dong, Xie, Yang, Choi, You-Jin, Tung, Hung-Chun, Chen, Xinyun, Xu, Meishu, Gibbs, Robert B., Poloyac, Samuel M., Liu, Silvia, Yu, Yanping, Luo, Jianhua, Liu, Youhua, Xie, Wen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2020
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351010/
https://ncbi.nlm.nih.gov/pubmed/32424001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019080767
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