Neutrophil Gelatinase–Associated Lipocalin Protects from ANCA-Induced GN by Inhibiting T(H)17 Immunity

BACKGROUND: Neutrophil gelatinase–associated lipocalin (NGAL) is a diagnostic marker of intrinsic kidney injury produced by damaged renal cells and by neutrophils. ANCA-associated vasculitis features necrotizing crescentic GN (NCGN), and ANCA-activated neutrophils contribute to NCGN. Whether NGAL pl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Schreiber, Adrian, Rousselle, Anthony, Klocke, Jan, Bachmann, Sebastian, Popovic, Suncica, Bontscho, Julia, Schmidt-Ott, Kai M., Siffrin, Volker, Jerke, Uwe, Ashraf, Muhammad Imtiaz, Panzer, Ulf, Kettritz, Ralph
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2020
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350985/
https://ncbi.nlm.nih.gov/pubmed/32487561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019090879
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