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Endothelial NF-κB Blockade Abrogates ANCA-Induced GN
ANCA-associated vasculitis (AAV) is a highly inflammatory condition in which ANCA-activated neutrophils interact with the endothelium, resulting in necrotizing vasculitis. We tested the hypothesis that endothelial NF-κB mediates necrotizing crescentic GN (NCGN) and provides a specific treatment targ...
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| Publicado no: | J Am Soc Nephrol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661273/ https://ncbi.nlm.nih.gov/pubmed/28687535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016060690 |
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