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CRISPR-Cas9 gene editing causes alternative splicing of the targeting mRNA

The technique of CRISPR-Cas9 gene editing has been widely used to specifically delete the selected target genes through generating double strand breaks (DSBs) and inducing insertion and/or deletion (indel) of the genomic DNAs in the cells. We recently applied this technique to disrupt mineral dust-i...

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Podrobná bibliografie
Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Zhang, Qian, Fu, Yao, Thakur, Chitra, Bi, Zhuoyue, Wadgaonkar, Priya, Qiu, Yiran, Xu, Liping, Rice, M’Kya, Zhang, Wenxuan, Almutairy, Bandar, Chen, Fei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350697/
https://ncbi.nlm.nih.gov/pubmed/32460957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.04.145
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