Two susceptible HLA-DRB1 alleles for multiple sclerosis differentially regulate anti-JC virus antibody serostatus along with fingolimod

BACKGROUND: Progressive multifocal leukoencephalopathy (PML) caused by JC virus (JCV) is a rare but serious complication of some disease-modifying drugs used to treat multiple sclerosis (MS). Japanese MS patients treated with fingolimod were reported to be 10 times more likely to develop PML than eq...

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Udgivet i:J Neuroinflammation
Main Authors: Watanabe, Mitsuru, Nakamura, Yuri, Isobe, Noriko, Tanaka, Masami, Sakoda, Ayako, Hayashi, Fumie, Kawano, Yuji, Yamasaki, Ryo, Matsushita, Takuya, Kira, Jun-ichi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350631/
https://ncbi.nlm.nih.gov/pubmed/32646493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01865-7
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