Peripheral Blood T Cell Dynamics Predict Relapse in Multiple Sclerosis Patients on Fingolimod

BACKGROUND: Fingolimod efficiently reduces multiple sclerosis (MS) relapse by inhibiting lymphocyte egress from lymph nodes through down-modulation of sphingosine 1-phosphate (S1P) receptors. We aimed to clarify the alterations in peripheral blood T cell subsets associated with MS relapse on fingoli...

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Pubblicato in:PLoS One
Autori principali: Song, Zi-Ye, Yamasaki, Ryo, Kawano, Yuji, Sato, Shinya, Masaki, Katsuhisa, Yoshimura, Satoshi, Matsuse, Dai, Murai, Hiroyuki, Matsushita, Takuya, Kira, Jun-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412716/
https://ncbi.nlm.nih.gov/pubmed/25919001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124923
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