Genetic and Infectious Profiles Influence Cerebrospinal Fluid IgG Abnormality in Japanese Multiple Sclerosis Patients

BACKGROUND: Abnormal intrathecal synthesis of IgG, reflected by cerebrospinal fluid (CSF) oligoclonal IgG bands (OBs) and increased IgG index, is much less frequently observed in Japanese multiple sclerosis (MS) cohorts compared with Western cohorts. We aimed to clarify whether genetic and common in...

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Detalhes bibliográficos
Main Authors: Yoshimura, Satoshi, Isobe, Noriko, Matsushita, Takuya, Masaki, Katsuhisa, Sato, Shinya, Kawano, Yuji, Ochi, Hirofumi, Kira, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988235/
https://ncbi.nlm.nih.gov/pubmed/24736746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095367
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