Genetic and Infectious Profiles Influence Cerebrospinal Fluid IgG Abnormality in Japanese Multiple Sclerosis Patients

BACKGROUND: Abnormal intrathecal synthesis of IgG, reflected by cerebrospinal fluid (CSF) oligoclonal IgG bands (OBs) and increased IgG index, is much less frequently observed in Japanese multiple sclerosis (MS) cohorts compared with Western cohorts. We aimed to clarify whether genetic and common in...

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Main Authors: Yoshimura, Satoshi, Isobe, Noriko, Matsushita, Takuya, Masaki, Katsuhisa, Sato, Shinya, Kawano, Yuji, Ochi, Hirofumi, Kira, Jun-ichi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988235/
https://ncbi.nlm.nih.gov/pubmed/24736746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095367
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