Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Opioid abuse alters the functions of immune cells in both in vitro and in vivo systems, including macrophages. Here, we investigated the effects of methadone, a widely used opioid receptor agonist for treatment of opiate addiction, on the expression of intracellular viral restriction factors and HIV...

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發表在:Front Immunol
Main Authors: Wang, Mei-Rong, Wu, Di-Di, Luo, Fan, Zhong, Chao-Jie, Wang, Xin, Zhu, Ni, Wu, Ying-Jun, Hu, Hai-Tao, Feng, Yong, Wang, Xu, Xiong, Hai-Rong, Hou, Wei
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350609/
https://ncbi.nlm.nih.gov/pubmed/32719674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01253
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