Methadone Inhibits Viral Restriction Factors and Facilitates HIV Infection in Macrophages

Opioid abuse alters the functions of immune cells in both in vitro and in vivo systems, including macrophages. Here, we investigated the effects of methadone, a widely used opioid receptor agonist for treatment of opiate addiction, on the expression of intracellular viral restriction factors and HIV...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Wang, Mei-Rong, Wu, Di-Di, Luo, Fan, Zhong, Chao-Jie, Wang, Xin, Zhu, Ni, Wu, Ying-Jun, Hu, Hai-Tao, Feng, Yong, Wang, Xu, Xiong, Hai-Rong, Hou, Wei
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350609/
https://ncbi.nlm.nih.gov/pubmed/32719674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01253
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